3 For this is the will of God, your sanctification: that you should abstain from sexual immorality; 4 that each of you should know how to possess his own vessel in sanctification and honor, 5 not in passion of lust, like the Gentiles who do not know God (1 Thessalonians 4:3–5, NKJV)
God has always called His people to holiness: “Be holy, for I am holy” (Lev. 11:44; 1 Pet. 1:16). Sanctification is a state of purity, set apart from defilement and dedicated to God and His service. This includes keeping our bodies from fornication (sexual immorality). To do that, the Lord calls on us to refuse the “passion of lust” that generates sexual sins (Matt. 5:28; Mk. 7:21). God expects us to “possess” (gain control over) our bodies by renewing our minds (Rom. 12:2). By doing so we can use our bodies in holy ways that honor God. On the other hand, those who do not know God live to satisfy their fleshly lusts. By doing so, they dishonor themselves and God. But, Christians are called out of sin’s defilement to be holy and pure in mind and body.